Rna Interference

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Contents

Indications

  • useful for identifying molecular targets for treatment of disease [1]

Principle

Clinical-significance

Notes

More General Terms

Additional Terms

References

  1. Wang T et al. Genetic screens in human cells using the CRISPR-Cas9 system. Science 2014 Jan 3; 343:80 <PubMed> PMID: [1] <Internet> [2]
    - Shalem O et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 2014 Jan 3; 343:84. <PubMed> PMID: [3] <Internet> [4]
  2. Niu Y et al. Generation of gene-modified cynomolgus monkey via Cas9/RNA- mediated gene targeting in one-cell embryos. Cell 2014 Jan 30; <PubMed> PMID: [5] <Internet> [6]
    - Pennisi E. Transgenic animals. Editing of targeted genes proved possible in monkeys. Science 2014 Jan 31; 343:476 PMID: [7]

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