Microsatellite Instability

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Contents

Introduction

Epidemiology

Pathology

Genetics

Management

More General Terms

Additional Terms

References

  1. Journal Watch 25(16):130, 2005 Hammock EA, Young LJ. Microsatellite instability generates diversity in brain and sociobehavioral traits. Science. 2005 Jun 10;308(5728):1630-4. PMID: [1]
  2. Kim GP, Colangelo LH, Wieand HS, Paik S, Kirsch IR, Wolmark N, Allegra CJ; National Cancer Institute. Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study. J Clin Oncol. 2007 Mar 1;25(7):767-72. Epub 2007 Jan 16. PMID: [2]
  3. Bankhead C FDA Breaks New Ground with Expanded Keytruda Indication - Pembrolizumab for genetic defect, not tumor type. MedPage Today. May 23, 2017 [3]
  4. Bankhead C More Cancers Seem to Harbor Lynch Syndrome Broader testing implied by 'practice-changing' study. MedPage Today. June 03, 2018 [4]
    - Schwark AL, et al Pan-cancer microsatellite instability predicts for presence of Lynch syndrome. American Society of Clinical Oncology (ASCO) 2018; Abstract LBA1509

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