Glial Neoplasm


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More Specific Terms


  • 50% of all primary brain neoplasms
  • most commonly occur in 4th-6th decade of life
  • grade 3 & 4 most commonly occur in patients 40-70 years





  • low-grade gliomas appear lesions with


  • low grade, grows slowly
  • inevitably transforms into higher grade if left untreated


More General Terms


  1. Medical Knowledge Self Assessment Program (MKSAP) 15, 16, 17. American College of Physicians, Philadelphia 2009, 2012, 2015
  2. Kaloshi G et al. Supratentorial low-grade gliomas in older patients. Neurology 2009 Dec 15; 73:2093. PMID: [1]
  3. Smith JS, Chang EF, Lamborn KR et al Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. J Clin Oncol. 2008 Mar 10;26(8):1338-45 PMID: [2]
  4. Surma-aho O, Niemelä M, Vilkki J et al Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients. Neurology. 2001 May 22;56(10):1285-90. PMID: [3]
  5. Weller M, Stupp R, Hegi ME et al Personalized care in neuro-oncology coming of age: why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice. Neuro Oncol. 2012 Sep;14 Suppl 4:iv100-8 PMID: [4]
  6. National Guideline Clearinghouse Low-grade astrocytomas and oligodendrogliomas. Alberta Health Services, Cancer Care ngc-guideline: [5]
    - The use of dexamethasone in patients with high grade gliomas. CancerControl Alberta ngc-guideline: [6]

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